beta-N-Acetylhexosaminidases

A hexosaminidase specific for non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides. It acts on GLUCOSIDES; GALACTOSIDES; and several OLIGOSACCHARIDES. Two specific mammalian isoenzymes of beta-N-acetylhexoaminidase are referred to as HEXOSAMINIDASE A and HEXOSAMINIDASE B. Deficiency of the type A isoenzyme causes TAY-SACHS DISEASE, while deficiency of both A and B isozymes causes SANDHOFF DISEASE. The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease.

Also Known As:

N-Acetyl-beta-D-hexosaminidase; beta-Hexosaminidase; beta-N-Acetyl-D-hexosaminidase; beta-N-Acetyl-hexosaminidase; N Acetyl beta D hexosaminidase; beta Hexosaminidase; beta N Acetyl D hexosaminidase; beta N Acetyl hexosaminidase; beta N Acetylhexosaminidase; beta N Acetylhexosaminidases; beta-N-Acetylhexosaminidase; beta-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase

Enzymes and Coenzymes: 1
- Enzymes: 155591
  - Hydrolases: 2206
    - Glycoside Hydrolases: 890
      - Hexosaminidases: 1050
        beta-N-Acetylhexosaminidases: 441

Masuo Ozaki Selected Research

Masuo Ozaki Research Topics

Disease

Drug/Important Bio-Agent (IBA)